Browsing by Author "Fasching PA"

Now showing items 1-3 of 3

    • Fine-Mapping of the 1p11.2 Breast Cancer Susceptibility Locus 

      Horne HN; Chung CC; Zhang H; Yu K; Prokunina-Olsson L; Michailidou K; Bolla MK; Wang Q; Dennis J; Hopper JL; Southey MC; Schmidt MK; Broeks A; Muir K; Lophatananon A; Fasching PA; Beckmann MW; Fletcher O; Johnson N; Sawyer EJ; Tomlinson I et al. (Incl. Kosma Veli-Matti; Mannermaa Arto) (Public Library of Science (PLoS), 2016)
      The Cancer Genetic Markers of Susceptibility genome-wide association study (GWAS) originally identified a single nucleotide polymorphism (SNP) rs11249433 at 1p11.2 associated with breast cancer risk. To fine-map this locus, ...
      info:eu-repo/semantics/article

    • Gene-environment interactions involving functional variants: Results from the Breast Cancer Association Consortium 

      Barrdahl M; Rudolph A; Hopper JL; Southey MC; Broeks A; Fasching PA; Beckmann MW; Gago-Dominguez M; Castelao JE; Guénel P; Truong T; Bojesen SE; Gapstur SM; Gaudet MM; Brenner H; Arndt V; Brauch H; Hamann U; Mannermaa A; Lambrechts D et al (Wiley-Blackwell, 2017)
      Investigating the most likely causal variants identified by fine-mapping analyses may improve the power to detect gene–environment interactions. We assessed the interplay between 70 single nucleotide polymorphisms identified ...
      info:eu-repo/semantics/article

    • TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer 

      Fagerholm R; Khan S; Schmidt MK; García-Closas M; Heikkilä P; Saarela J; Beesley J; Jamshidi M; Aittomäki K; Liu J; Ali HR; Andrulis IL; Beckmann MW; Behrens S; Blows FM; Brenner H; Chang-Claude J; Couch FJ; Czene K; Fasching PA; et al [Incl Kosma V-M] (Impact Journals, LLC, 2017)
      TP53 overexpression is indicative of somatic TP53 mutations and associates with aggressive tumors and poor prognosis in breast cancer. We utilized a two-stage SNP association study to detect variants associated with breast ...
      info:eu-repo/semantics/article