Browsing by Author "Grodzinsky, Alan J"
Now showing items 1-2 of 2
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Cyclic loading regime considered beneficial does not protect injured and interleukin-1-inflamed cartilage from post-traumatic osteoarthritis
Eskelinen, Atte SA; Florea, Cristina; Tanska, Petri; Hung, Han-Hwa K; Frank, Eliot H; Mikkonen, Santtu; Nieminen, Petteri; Julkunen, Petro; Grodzinsky, Alan J; Korhonen, Rami K (Elsevier Ltd, 2022)Injurious overloading and inflammation perturbate homeostasis of articular cartilage, leading to abnormal tissue-level loading during post-traumatic osteoarthritis. Our objective was to gain time- and cartilage depth-dependent ...
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Shear strain and inflammation-induced fixed charge density loss in the knee joint cartilage following ACL injury and reconstruction: A computational study
Orozco, Gustavo A; Eskelinen, Atte SA; Kosonen, Joonas P; Tanaka, Matthew S; Yang, Mingrui; Link, Thomas M; Ma, Benjamin; Li, Xiaojuan; Grodzinsky, Alan J; Korhonen, Rami K; Tanska, Petri (Wiley, 2021)Excessive tissue deformation near cartilage lesions and acute inflammation within the knee joint after anterior cruciate ligament (ACL) rupture and reconstruction surgery accelerate the loss of fixed charge density (FCD) ...Tieteelliset aikakauslehtiartikkelit