Browsing by Author "Kaprio J"

Now showing items 1-4 of 4

    • Genome-wide association study in Finnish twins highlights the connection between nicotine addiction and neurotrophin signaling pathway 

      Hällfors J; Palviainen T; Surakka I; Gupta R; Buchwald J; Raevuori A; Ripatti S; Korhonen T; Jousilahti P; Madden PAF; Kaprio J; Loukola A (Wiley-Blackwell, 2019)
      The heritability of nicotine dependence based on family studies is substantial. Nevertheless, knowledge of the underlying genetic architecture remains meager. Our aim was to identify novel genetic variants responsible for ...
      Tieteelliset aikakauslehtiartikkelit

    • Mendelian randomisation analysis strongly implicates adiposity with risk of developing colorectal cancer 

      Jarvis D; Mitchell JS; Law PJ; Palin K; Tuupanen S; Gylfe A; Hänninen UA; Cajuso T; Tanskanen T; Kondelin J; Kaasinen E; Sarin A-P; Kaprio J; Eriksson JG; Rissanen H; Knekt P; Pukkala E; Jousilahti P; Salomaa V; Ripatti S; Palotie A; Järvinen H; Renkonen-Sinisalo L; Lepistö A; Böhm J; Meklin J-P; Al-Tassan NA; Palles C; Martin L; Barclay E; Farrington SM; Timofeeva MN; Meyer BF; Wakil SM; Campbell H; Smith C.G; Idziaszczyk S; Maughan TS; Kaplan R; Kerr R; Kerr D; Buchanan DD; Win AK; Hopper JL; Jenkins MA; Lindor NM; Newcomb PA (Cancer Research UK, 2016)
      Background: Observational studies have associated adiposity with an increased risk of colorectal cancer (CRC). However, such studies do not establish a causal relationship. To minimise bias from confounding we performed ...
      info:eu-repo/semantics/article

    • Neuregulin signaling pathway in smoking behavior 

      Gupta R; Qaiser B; He L; Hiekkalinna TS; Zheutlin AB; Therman S; Ollikainen M; Ripatti S; Perola M; Salomaa V; Milani L; Cannon TD; Madden PAF; Korhonen T; Kaprio J; Loukola A. (Springer Nature, 2017)
      Understanding molecular processes that link comorbid traits such as addictions and mental disorders can provide novel therapeutic targets. Neuregulin signaling pathway (NSP) has previously been implicated in schizophrenia, ...
      info:eu-repo/semantics/article

    • Prospective association between tobacco smoking and death by suicide: a competing risks hazard analysis in a large twin cohort with 35-year follow-up 

      Evins AE; Korhonen T; Kinnunen TH; Kaprio J (Cambridge University Press (CUP), 2017)
      The relationship between smoking and suicide remains controversial. A total of 16 282 twin pairs born before 1958 in Finland and alive in 1974 were queried with detailed health and smoking questionnaires in 1975 and 1981, ...
      info:eu-repo/semantics/article