Browsing by Subject "PXR"
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Activation of nuclear receptor PXR impairs glucose tolerance and dysregulates GLUT2 expression and subcellular localization in liver
(Elsevier BV, 2018)Pregnane X receptor (PXR) is a nuclear receptor that senses chemical environment and is activated by numerous clinically used drugs and environmental contaminants. Previous studies have indicated that several drugs known ...Tieteelliset aikakauslehtiartikkelit
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Pregnane X receptor activation remodels glucose metabolism to promote NAFLD development in obese mice
(Elsevier GmbH, 2023)Objective Both obesity and exposure to chemicals may induce non-alcoholic fatty liver disease (NAFLD). Pregnane X Receptor (PXR) is a central target of metabolism disrupting chemicals and disturbs hepatic glucose and lipid ...
