Browsing by Subject "QSPR"
Now showing items 1-4 of 4
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Corneal and conjunctival drug permeability : systematic comparison and pharmacokinetic impact in the eye
(Elsevier BV, 2018)On the surface of the eye, both the cornea and conjunctiva are restricting ocular absorption of topically applied drugs, but barrier contributions of these two membranes have not been systemically compared. Herein, we ...Tieteelliset aikakauslehtiartikkelit
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Correlation between calculated molecular descriptors of excipient amino acids and experimentally observed thermal stability of lysozyme
(, 2017)A quantitative structure-property relationship (QSPR) between protein stability and the physicochemical properties of excipients was investigated to enable a more rational choice of stabilizing excipients than prior ...info:eu-repo/semantics/article
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Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model
(Elsevier BV, 2017)Conjunctiva occupies most of the ocular surface area, and conjunctival permeability affects ocular and systemic drug absorption of topical ocular medications. Therefore, the aim of this study was to obtain a computational ...info:eu-repo/semantics/article
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Prediction of ocular drug distribution from systemic blood circulation
(American Chemical Society, 2016)Systemically circulating drugs may distribute to ocular tissues across the blood-ocular barriers. Ocular distribution is utilized in the treatment of ocular diseases with systemic medications, but ocular delivery of systemic ...article
