Browsing by Subject "arylpiperazine"

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    • Discovery of novel arylpiperazine-based DA/5-HT modulators as potential antipsychotic agents – Design, synthesis, structural studies and pharmacological profiling 

      Stępnicki, Piotr; Targowska-Duda, Katarzyna M.; Martínez, Antón L.; Zięba, Agata; Wronikowska-Denysiuk, Olga; Wróbel, Martyna Z; Bartyzel, Agata; Trzpil, Alicja; Wróbel, Tomasz M; Chodkowski, Andrzej; Mirecka, Karolina; Karcz, Tadeusz; Szczepańska, Katarzyna; Loza, Maria I; Budzyńska, Barbara; Turło, Jadwiga; Handzlik, Jadwiga; Fornal, Emilia; Poleszak, Ewa; Castro, Marián; Kaczor, Agnieszka A (Elsevier Masson SAS, 2023)
      Schizophrenia is a mental disorder with a complex pathomechanism involving many neurotransmitter systems. Among the currently used antipsychotics, classical drugs acting as dopamine D2 receptor antagonists, and drugs of a ...