Browsing by Subject "inflammation"
Now showing items 1-20 of 43
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Acute Inflammatory Response Following Increased Blood-Brain Barrier Permeability Induced by Focused Ultrasound is Dependent on Microbubble Dose
(Ivyspring International Publisher, 2017)Rationale: Focused ultrasound (FUS), in conjunction with circulating microbubbles (MBs), can be used to transiently increase the permeability of the blood-brain barrier (BBB) in a targeted manner, allowing therapeutic ...info:eu-repo/semantics/article
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An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study
(MDPI AG, 2019)A healthy dietary pattern is associated with a lower risk of metabolic syndrome (MetS) and reduced inflammation. To explore this at the molecular level, we investigated the effect of a Nordic diet (ND) on changes in the ...Tieteelliset aikakauslehtiartikkelit
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Associations of physical activity, sedentary time, and diet quality with biomarkers of inflammation in children
(Informa UK Limited, 2021)We investigated the associations of physical activity (PA), sedentary time (ST), and diet quality with biomarkers of inflammation in 390 children (192 girls, 198 boys) aged 6–8 years. PA energy expenditure (PAEE), light ...Tieteelliset aikakauslehtiartikkelit
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Biologiset lääkkeet tulehduksellisten suolistosairauksien hoidossa Kuopion yliopistollisessa sairaalassa vuosina 2019-2022
(Itä-Suomen yliopisto; University of Eastern Finland, 2022)info:eu-repo/semantics/masterThesis
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Cardiorespiratory Fitness, Inflammation, and Risk of Chronic Obstructive Pulmonary Disease in Middle-Aged Men: A COHORT STUDY
(Wolters Kluwer Health, Inc., 2022)Purpose: Chronic obstructive pulmonary disease (COPD) is characterized by chronic lung inflammation. The relationship between cardiorespiratory fitness (CRF) and COPD has not been well characterized. We aimed to evaluate ...
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Cellular mechanisms of valvular thickening in early and intermediate calcific aortic valve disease
(Bentham Science Publishers Ltd., 2018)Background: Calcific aortic valve disease is common in an aging population. It is an active atheroinflammatory process that has an initial pathophysiology and similar risk factors as atherosclerosis. However, the ultimate ...Tieteelliset aikakauslehtiartikkelit
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Cerebellar Atrophy and Changes in Cytokines Associated with the CACNA1A R583Q Mutation in a Russian Familial Hemiplegic Migraine Type 1 Family
(Frontiers Media SA, 2017)Background: Immune mechanisms recently emerged as important contributors to migraine pathology with cytokines affecting neuronal excitation. Therefore, elucidating the profile of cytokines activated in various forms of ...info:eu-repo/semantics/article
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CuII(atsm) Attenuates Neuroinflammation
(Frontiers Media SA, 2018)Background: Neuroinflammation and biometal dyshomeostasis are key pathological features of several neurodegenerative diseases, including Alzheimer’s disease (AD). Inflammation and biometals are linked at the molecular level ...Tieteelliset aikakauslehtiartikkelit
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Cyclic loading regime considered beneficial does not protect injured and interleukin-1-inflamed cartilage from post-traumatic osteoarthritis
(Elsevier Ltd, 2022)Injurious overloading and inflammation perturbate homeostasis of articular cartilage, leading to abnormal tissue-level loading during post-traumatic osteoarthritis. Our objective was to gain time- and cartilage depth-dependent ...
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Deletion of the murine ortholog of human 9p21.3 locus promotes atherosclerosis by increasing macrophage proinflammatory activity
(Frontiers Media S.A, 2023)Background: Several genome-wide association studies have reported a risk locus for coronary artery disease (CAD) in the 9p21. 3 chromosomal region. This region encodes a lncRNA in the INK4 locus (ANRIL) and its genetic ...
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Design of coumarin derivatives of transient receptor potential ankyrin 1 antagonists
(Itä-Suomen yliopisto; University of Eastern Finland, 2022)info:eu-repo/semantics/masterThesis
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Effect of haematopoietic GPR35 deletion on atherosclerotic aortic valve disease in hypercholesterolemic mouse model
(Itä-Suomen yliopisto; University of Eastern Finland, 2023)info:eu-repo/semantics/masterThesis
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Effects of dipeptidyl peptidase 4 inhibition on inflammation in atherosclerosis: A 18F-fluorodeoxyglucose study of a mouse model of atherosclerosis and type 2 diabetes
(Elsevier BV, 2020)Background and aims Dipeptidyl peptidase 4 (DPP-4) inhibitors have anti-inflammatory and atheroprotective effects. We evaluated the effects of the DPP-4 inhibitor linagliptin on atherosclerotic plaque and hepatic inflammation ...Tieteelliset aikakauslehtiartikkelit
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Emissions and atmospheric processes influence the chemical composition and toxicological properties of urban air particulate matter in Nanjing, China
(Elsevier BV, 2018)Ambient inhalable particulate matter (PM) is a serious health concern worldwide, but especially so in China where high PM concentrations affect huge populations. Atmospheric processes and emission sources cause spatial and ...Tieteelliset aikakauslehtiartikkelit
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Extracellular vesicle-mediated crosstalk between adipose tissue and breast cancer
(Itä-Suomen yliopisto; University of Eastern Finland, 2023)info:eu-repo/semantics/masterThesis
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Extracellular vesicles are integral and functional components of the extracellular matrix
(Elsevier BV, 2019)Extracellular vesicles (EV) are small plasma membrane-derived particles released into the extracellular space by virtually all cell types. Recently, EV have received increased interest because of their capability to carry ...Tieteelliset aikakauslehtiartikkelit
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Fatty acids and oxidized lipoproteins contribute to autophagy and innate immunity responses upon the degeneration of retinal pigment epithelium and development of age-related macular degeneration
(Elsevier BV, 2019)Retinal pigment epithelium (RPE) damage is a primary sign in the development of age-related macular degeneration (AMD) the leading cause of blindness in western countries. RPE cells are exposed to chronic oxidative stress ...Tieteelliset aikakauslehtiartikkelit
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Hyaluronan synthase 1 : a mysterious enzyme with unexpected functions
(Frontiers Media SA, 2015)Hyaluronan synthase 1 (HAS1) is one of three isoenzymes responsible for cellular hyaluronan synthesis. Interest in HAS1 has been limited because its role in hyaluronan production seems to be insignificant compared to the ...info:eu-repo/semantics/article
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Imaging biomarkers of epileptogenecity after traumatic brain injury - Preclinical frontiers
(Elsevier BV, 2019)Posttraumatic epilepsy (PTE) is a major neurodegenerative disease accounting for 20% of symptomatic epilepsy cases. A long latent phase offers a potential window for prophylactic treatment strategies to prevent epilepsy ...Tieteelliset aikakauslehtiartikkelit
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Inverse association between serum albumin and future risk of venous thromboembolism: Interrelationship with high sensitivity C-reactive protein
(Informa UK Limited, 2018)Purpose: We aimed to assess the prospective association of serum albumin with venous thromboembolism (VTE) risk and evaluate if the association is independent of or modified by inflammation, as measured by high sensitivity ...Tieteelliset aikakauslehtiartikkelit