Time-dependent inhibition of CYP3A4 – Method set-up to determine kinetic parameters KI and kinact

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Date
2024-06-26
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Vilja, Mitja

Masters thesis 

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Publisher
University of Eastern Finland 
Faculty of Health Sciences, School of Pharmacy 
biopharmacy 
Keywords
biofarmasia   entsyymit   lääkeaineet   biopharmacy   enzymes   medicinal substances   enzymer   läkemedelssubstanser   CYP3A4   drug-drug interaction   lääkeaineinteraktio   time-dependent inhibition   aikariippuvainen inhibitio   kinetic parameters   kineettiset parametrit   KI   kinact   IC50 shift   IC50 siirtymä   
URI
http://urn.fi/urn:nbn:fi:uef-20241380
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