Browsing by Subject "traumatic brain injury"
Now showing items 1-8 of 8
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Acute downregulation of novel hypothalamic protein sushi repeat-containing protein X-Linked 2 (SRPX2) after experimental traumatic brain injury
(Mary Ann Liebert Inc, 2019)Traumatic brain injury (TBI) causes damage to the hypothalamo-hypophyseal axis, leading to endocrine dysregulation in up to 40% of TBI patients. Hence, there is an urgent need to identify non-invasive biomarkers for ...Tieteelliset aikakauslehtiartikkelit
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Algorithm for automatic detection of spontaneous seizures in rats with post-traumatic epilepsy
(Elsevier BV, 2018)Background Labor intensive electroencephalogram (EEG) analysis is a major bottleneck to identifying anti-epileptogenic treatments in experimental models of post-traumatic epilepsy. We aimed to develop an algorithm for ...Tieteelliset aikakauslehtiartikkelit
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Elevated acute plasma miR-124-3p level relates to evolution of larger cortical lesion area after traumatic brain injury
(Elsevier BV, 2020)Mechanisms initiated by traumatic brain injury (TBI), leading to the development of progressive secondary injury are poorly understood. MicroRNAs (miRNAs) have a proposed role in orchestrating the post-injury aftermath as ...Tieteelliset aikakauslehtiartikkelit
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Harmonization of lateral fluid-percussion injury model production and post-injury monitoring in a preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis
(Elsevier BV, 2019)Multi-center preclinical studies can facilitate the discovery of biomarkers of antiepileptogenesis and thus facilitate the diagnosis and treatment development of patients at risk of developing post-traumatic epilepsy. ...Tieteelliset aikakauslehtiartikkelit
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Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis
(Elsevier BV, 2019)Preclinical imaging studies of posttraumatic epileptogenesis (PTE) have largely been proof-of-concept studies with limited animal numbers, and thus lack the statistical power for biomarker discovery. Epilepsy Bioinformatics ...Tieteelliset aikakauslehtiartikkelit
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Harmonization of the pipeline for seizure detection to phenotype post-traumatic epilepsy in a preclinical multicenter study on post-traumatic epileptogenesis
(, 2019)Rationale The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx) Centre without walls is an NIH funded multicenter consortium. One of EpiBioS4Rx projects is a preclinical post-traumatic epileptogenesis ...Tieteelliset aikakauslehtiartikkelit
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Psychotropic medication after intensive care unit treated pediatric traumatic brain injury
(Elsevier BV, 2020)Background Our aim was to assess the occurrence and risk factors for psychotropic medication use after pediatric traumatic brain injury treated in the intensive care unit. Methods We combined data from the Finnish ...Tieteelliset aikakauslehtiartikkelit
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Quantitative susceptibility mapping of the rat brain after traumatic brain injury
(Wiley, 2021)The primary lesion arising from the initial insult after traumatic brain injury (TBI) triggers a cascade of secondary tissue damage, which may also progress to connected brain areas in the chronic phase. The aim of this ...Tieteelliset aikakauslehtiartikkelit
