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Different rhinologic diseases cause a similar multidimensional decrease in generic health-related quality of life

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Date
2018
Author(s)
Ylitalo-Heikkilä, Maija
Virkkula, Paula
Sintonen, Harri
Lundberg, Marie
Roine, Risto P
Hytönen, Maija
Unique identifier
10.1111/coa.13190
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Citation
Ylitalo-Heikkilä, Maija. Virkkula, Paula. Sintonen, Harri. Lundberg, Marie. Roine, Risto P. Hytönen, Maija. (2018). Different rhinologic diseases cause a similar multidimensional decrease in generic health-related quality of life.  CLINICAL OTOLARYNGOLOGY, [First published: 2 Sept 2018], 1-7. 10.1111/coa.13190.
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© John Wiley & Sons Ltd
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Abstract

Background
Previous studies illustrated that chronic rhinosinusitis and allergic rhinitis represent individual and socioeconomic burdens to a patient. However, few studies exist on the health‐related quality of life (HRQoL) amongst other rhinologic patients. Our study investigated the generic HRQoL in different rhinologic diseases.

Methodology
Unselected adult rhinologic patients requiring special care at the Helsinki University Hospital were enrolled in this cross‐sectional, questionnaire‐based prospective study in February, May, August and November 2014. Patients were mailed a medical history questionnaire and a generic 15‐dimension (15D) HRQoL questionnaire. Diagnostic data were collected from electronic patient records following outpatient visits. Patient HRQoL scores were compared to an age‐ and sex‐standardised general population sample obtained from a large national health examination survey.

Results
This study consisted of 337 rhinologic patients (mean age 50.2 years, 50.4% men). The mean 15D score amongst rhinologic patients (0.865) was both statistically significant and clinically poorer than that amongst the general population (0.929). Rhinologic patients fared poorly on most dimensions of the 15D instrument, particularly on sleep, discomfort and symptoms, breathing and vitality. Patients with obstructive sleep apnoea (OSA) were particularly affected. Yet, comparing the five most common rhinologic diagnostic groups revealed no significant differences in the mean 15D scores.

Conclusions
Rhinologic diseases, independent of the underlying cause, substantially and negatively affect patients’ HRQoL. OSA decreases HRQoL in these patients, although patients without an OSA diagnosis still suffer from a clinically important impairment of HRQoL and poor quality sleep.

URI
https://erepo.uef.fi/handle/123456789/6934
Link to the original item
http://dx.doi.org/10.1111/coa.13190
Publisher
Wiley
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  • Yhteiskuntatieteiden ja kauppatieteiden tiedekunta [369]
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