• Random forest-based imputation outperforms other methods for imputing LC-MS metabolomics data: a comparative study 

  Kokla, M; Virtanen, J; Kolehmainen, M; Paananen, J; Hanhineva, K (2019)

  Background LC-MS technology makes it possible to measure the relative abundance of numerous molecular features of a sample in single analysis. However, especially non-targeted metabolite profiling approaches generate vast ...

• An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study 

  Ulven, SM; Holven, KB; Rundblad, A; Myhrstad, MCW; Leder, L; Dahlman, I; Mello, VD; Schwab, U; Carlberg, C; Pihlajamäki, J; Hermansen, K; Dragsted, LO; Gunnarsdottir, I; Cloetens, L; Åkesson, B; Rosqvist, F; Hukkanen, J; Herzig, KH; Savolainen, MJ; Risérus, U; et al. incl. Uusitupa, M (MDPI AGSveitsi, 2019)

  A healthy dietary pattern is associated with a lower risk of metabolic syndrome (MetS) and reduced inflammation. To explore this at the molecular level, we investigated the effect of a Nordic diet (ND) on changes in the ...

• Existence of Meromorphic Solutions of First-Order Difference Equations 

  Korhonen, Risto; Zhang, Yueyang (Springer Science and Business Media LLC, 2019)

  It is shown that if f(z+1)n=R(z,f), where R(z, f) is rational in f with meromorphic coefficients and degf(R(z,f))=n, has an admissible meromorphic solution, then either f satisfies a difference linear or Riccati equation ...

• As you sow, so shall you reap: Is there a ″golden standard″ to teach histology? 

  Felszeghy, S; Gilbert, G; Koskela, A; Nieminen, P; Sironen, R; Pasonen-Seppänen, S; Sointu, E; Morton, D; Mahonen, A (Association for Medical Education in Europe (AMEE), 2019)

• Lakes, presidents and shopping on mental maps: children's perceptions of the Finnish-Russian border and the borderland 

  Kaisto, Virpi; Brednikova, Olga (Fennia - International Journal of GeographySuomi, 2019)

  The Finnish–Russian borderland has transformed in the last three decades from two isolated national territories into a transition zone, where the ‘other’ culture and society is ever more present. This paper analyses what ...

• Eating Competence Is Associated with Lower Prevalence of Obesity and Better Insulin Sensitivity in Finnish Adults with Increased Risk for Type 2 Diabetes: The StopDia Study 

  Tilles-Tirkkonen, Tanja; Aittola, Kirsikka; Männikkö, Reija; Absetz, Pilvikki; Kolehmainen, Marjukka; Schwab, Ursula; Lindström, Jaana; Lakka, Timo; Pihlajamäki, Jussi; Karhunen, Leila (MDPI AGSveitsi, 2020)

  A healthy diet prevents type 2 diabetes but is often difficult to adhere to. This cross-sectional study aimed to investigate whether eating competence is associated with diet or risk factors and prevalence of type 2 diabetes ...

• Associations Between Attention-Deficit/Hyperactivity Disorder and Various Eating Disorders: A Swedish Nationwide Population Study Using Multiple Genetically Informative Approaches 

  Yao, Shuyang; Kuja-Halkola, Ralf; Martin, Joanna; Lu, Yi; Lichtenstein, Paul; Norring, Claes; Birgegård, Andreas; Yilmaz, Zeynep; Hübel, Christopher; Watson, Hunna; Baker, Jessica; Almqvist, Catarina; Eating Disorders Working Group of the Psychiatric Genomics Consortium; Thornton, Laura M; Magnusson, Patrik K; Bulik, Cynthia M; Larsson, Henrik [incl. Karhunen, L] (Elsevier BV, 2019)

  Background Although attention-deficit/hyperactivity disorder (ADHD) and eating disorders (EDs) frequently co-occur, little is known about the shared etiology. In this study, we comprehensively investigated the genetic ...

• Trajectories of self-rated health before and after retirement: evidence from two cohort studies 

  Stenholm, S; Virtanen, M; Pentti, J; Oksanen, T; Kivimäki, M; Vahtera, J (BMJ, 2019)

  Objectives Previous studies have produced conflicting findings on the health consequences of retirement. We aimed at identifying trajectories of self-rated health over retirement transition using repeated measurements ...

• Opioid Use After Hospital Care due to Hip Fracture Among Community-Dwelling Persons With and Without Alzheimer's Disease 

  Lintula, E; Tiihonen, M; Taipale, H; Tolppanen, AM; Tanskanen, A; Tiihonen, J; Hartikainen, S; Hamina, A (Springer Science and Business Media LLCSveitsi, 2019)

  Background Hip fractures are common among persons with Alzheimer’s disease (AD), but problems in pain assessment may lead to insufficient analgesia after hospitalization. Objective We investigated the prevalence of ...

• Itsemurhariskissä olevan ikäihmisen kanssa työskentelyssä vaaditut taidot - katsausartikkeli kansainvälisestä tutkimuksesta 

  Ylinen, Satu; Valokivi, Heli, Rissanen, Sari; Kalliomaa-Puha; Laura (GerontologiaSuomi, 2019)

  Tämän artikkelin tavoitteena on tuottaa kirjallisuuskatsauksen avulla sosiaalityön käytännön ja tutkimuksen kannalta merkityksellistä tietoa ikäihmisten itsemurhista. Millaisia iäkkäiden henkilöiden itsemurhan riskitekijöitä ...

• Meeting the Spiritual Care Needs of Emerging Adults with Cancer 

  Saarelainen, Suvi-Maria (MDPI AGSveitsi, 2020)

  Every year 90,000 young people in Europe and the USA are newly diagnosed with cancer. The majority of earlier studies have taken a quantitative perspective, rarely focusing on the importance of religiosity and spirituality. ...

• Clandestine migrant mobility, European peripheries, and practical cosmopolitanism in Fabienne Kanor's Faire l'aventure 

  Toivanen, Anna-Leena (Liverpool University Press, 2019)

  The present article focuses on the representation of clandestine migrant mobilities in the novel Faire l’aventure by the Franco-Caribbean author Fabienne Kanor. The analysis has two lines of inquiry. Firstly, it focuses ...

• Transferability and calibration of airborne laser scanning based mixed-effects models to estimate the attributes of sawlog-sized Scots pines 

  Korhonen, L; Repola, J; Karjalainen, T; Packalen, P; Maltamo, M (Finnish Society of Forest ScienceSuomi, 2019)

  Airborne laser scanning (ALS) data is nowadays often available for forest inventory purposes, but adequate field data for constructing new forest attribute models for each area may be lacking. Thus there is a need to study ...

• Triple Contrast CT Method Enables Simultaneous Evaluation of Articular Cartilage Composition and Segmentation 

  Honkanen, MKM; Saukko, AEA; Turunen, MJ; Xu, W; Lovric, G; Honkanen, JTJ; Grinstaff, MW; Lehto, VP; Töyräs, J (Springer Science and Business Media LLC, 2019)

  Early degenerative changes of articular cartilage are detected using contrast-enhanced computed tomography (CT) with a cationic contrast agent (CA). However, cationic CA diffusion into degenerated cartilage decreases with ...

• Synchrotron microCT reveals the potential of the dual contrast technique for quantitative assessment of human articular cartilage composition 

  Honkanen, MKM; Saukko, AEA; Turunen, MJ; Shaikh, R; Prakash, M; Lovric, G; Joukainen, A; Kröger, H; Grinstaff, MW; Töyräs, J (Wiley, 2019)

  Dual contrast micro computed tomography (CT) shows potential for detecting articular cartilage degeneration. However, the performance of conventional CT systems is limited by beam hardening, low image resolution (full‐body ...

• Imaging of Proteoglycan and Water Contents in Human Articular Cartilage with Full-Body CT Using Dual Contrast Technique 

  Honkanen, MKM; Matikka, H; Honkanen, JTJ; Bhattarai, A; Grinstaff, MW; Joukainen, A; Kröger, H; Jurvelin, JS; Töyräs, J (Wiley, 2019)

  Assessment of cartilage composition via tomographic imaging is critical after cartilage injury to prevent post‐traumatic osteoarthritis. Diffusion of cationic contrast agents in cartilage is affected by proteoglycan loss ...

• Fecal Sludge Derived Products as Fertilizer for Lettuce Cultivation in Urban Agriculture 

  Pradhan, Surendra K; Cofie, Olufunke; Nikiema, Josiane; Heinonen-Tanski, Helvi (MDPI AGSveitsi, 2019)

  Fecal sludge (FS) contains a significant amount of plant nutrients. FS (treated/untreated) has been used as soil ameliorant in several countries. Use of FS-based compost on lettuce may meet reservations due to possible ...

• Semisupervised Generative Autoencoder for Single-Cell Data 

  Ngo Trong, Trung; Mehtonen, Juha; González, Geraldo; Kramer, Roger; Hautamäki, Ville; Heinäniemi, Merja (Mary Ann Liebert Inc, 2019)

  Single-cell transcriptomics offers a tool to study the diversity of cell phenotypes through snapshots of the abundance of mRNA in individual cells. Often there is additional information available besides the single-cell ...

• Associations of IGF-1 and Adrenal Androgens with Cognition in Childhood 

  Mäntyselkä, A; Haapala, EA; Lindi, V; Häkkinen, MR; Auriola, S; Jääskeläinen, J; Lakka, TA (Sveitsi, 2019)

  Background: Little is known about the association between adrenarche and cognition in general populations of children. We therefore studied the associations of dehydroepiandrosterone sulfate (DHEAS), androstenedione (A4), ...

• Predicting Intelligence Based on Cortical WM/GM Contrast, Cortical Thickness and Volumetry 

  Valverde, JM; Imani, V; Lewis, JD; Tohka, J (Springer International Publishing, 2019)

  We propose a four-layer fully-connected neural network (FNN) for predicting fluid intelligence scores from T1-weighted MR images for the ABCD-challenge. In addition to the volumes of brain structures, the FNN uses cortical ...

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