Skip to main contentSkip to search and navigation

UEF eREPOSITORY

    • English
    • suomi
  • English 
    • English
    • suomi
  • Login
View Item 
  •   Home
  • Artikkelit
  • Luonnontieteiden ja metsätieteiden tiedekunta
  • View Item
  •   Home
  • Artikkelit
  • Luonnontieteiden ja metsätieteiden tiedekunta
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Comparison of water, hydroxyproline, uronic acid and elastin contents of bovine knee ligaments and patellar tendon and their relationships with biomechanical properties

Thumbnail
Files
Item embargoed until 2022-02-28. Restrictions imposed by the publisher
Self archived version
final draft
Date
2020
Author(s)
Ristaniemi, A
Torniainen, J
Stenroth, L
Finnilä, MAJ
Paakkonen, T
Töyräs, J
Korhonen, RK
Unique identifier
10.1016/j.jmbbm.2020.103639
Metadata
Show full item record
More information
Research Database SoleCris

Self-archived article

Citation
Ristaniemi, A. Torniainen, J. Stenroth, L. Finnilä, MAJ. Paakkonen, T. Töyräs, J. Korhonen, RK. (2020). Comparison of water, hydroxyproline, uronic acid and elastin contents of bovine knee ligaments and patellar tendon and their relationships with biomechanical properties.  Journal of the mechanical behavior of biomedical materials, 104, 103639. 10.1016/j.jmbbm.2020.103639.
Rights
© Elsevier Ltd
Licensed under
CC BY-NC-ND https://creativecommons.org/licenses/by-nc-nd/4.0/
Abstract

Mechanical material properties of ligaments originate from their biochemical composition and structural organization. However, it is not yet fully elucidated how biochemical contents vary between knee ligaments and patellar tendon (PT) and how they relate with mechanical properties. The purpose of this study was to compare water, collagen, proteoglycan and elastin contents between bovine knee ligaments and PT and correlate them with tensile material properties.

Hydroxyproline (collagen), uronic acid (proteoglycan) and elastin contents per wet and dry weights were measured using colorimetric biochemical methods for bovine knee ligament and PT samples (n = 10 knees). Direct comparison and correlation with multiple linear regression were performed against biomechanical properties measured in our earlier study.

Anterior cruciate ligament (ACL) and PT exhibited lower hydroxyproline content per wet weight compared with other ligaments (p < 0.05). Cruciate ligaments had higher uronic acid content per dry weight compared with collateral ligaments (p < 0.05). Posterior cruciate ligament had higher elastin content than ACL (p < 0.05). Higher hydroxyproline content per wet weight implied higher Young's modulus, strength and toughness. Quantitatively, higher elastin content per wet weight predicted higher toe region nonlinearity and Young's modulus whereas higher uronic acid content per dry weight predicted lower Young's modulus, yield stress and toughness.

Differences between ligaments in biochemical composition highlight differences in their physiological function and loading regimes. As expected, collagen content showed similar trend with stiffness and strength. The predictive role of proteoglycan and elastin contents on the mechanical properties might indicate their important functional role in ligaments.

Subjects
ligament   patellar tendon   knee joint   hydroxyproline   uronic acid   elastin   
URI
https://erepo.uef.fi/handle/123456789/8088
Link to the original item
http://dx.doi.org/10.1016/j.jmbbm.2020.103639
Publisher
Elsevier BV
Collections
  • Luonnontieteiden ja metsätieteiden tiedekunta [1139]
University of Eastern Finland
OpenAccess
eRepo
erepo@uef.fi
UEF Open Science
Accessibility in eRepo
Service provided by
the University of Eastern Finland Library
Library web pages
Twitter
Facebook
Youtube
Library blog
 sitemap
Search

Browse

All of the ArchiveResource types & CollectionsBy Issue DateAuthorsTitlesSubjectsFacultyDepartmentFull organizationSeriesMain subjectThis CollectionBy Issue DateAuthorsTitlesSubjectsFacultyDepartmentFull organizationSeriesMain subject

My Account

Login
University of Eastern Finland
OpenAccess
eRepo
erepo@uef.fi
UEF Open Science
Accessibility in eRepo
Service provided by
the University of Eastern Finland Library
Library web pages
Twitter
Facebook
Youtube
Library blog
 sitemap