Browsing Rinnakkaistallenteet by Author "O'Brien, TJ"
Now showing items 1-4 of 4
-
Harmonization of lateral fluid-percussion injury model production and post-injury monitoring in a preclinical multicenter biomarker discovery study on post-traumatic epileptogenesis
Ndode-Ekane, XE; Santana-Gomez, C; Casillas-Espinosa, PM; Ali, I; Brady, RD; Smith, G; Andrade, P; Immonen, R; Puhakka, N; Hudson, MR; Braine, EL; Shultz, SR; Staba, RJ; O'Brien, TJ; Pitkänen, A (Elsevier BV, 2019)Multi-center preclinical studies can facilitate the discovery of biomarkers of antiepileptogenesis and thus facilitate the diagnosis and treatment development of patients at risk of developing post-traumatic epilepsy. ...Tieteelliset aikakauslehtiartikkelit
-
Harmonization of pipeline for preclinical multicenter MRI biomarker discovery in a rat model of post-traumatic epileptogenesis
Immonen, R; Smith, G; Brady, RD; Wright, D; Johnston, L; Harris, NG; Manninen, E; Salo, R; Branch, C; Duncan, D; Cabeen, R; Ndode-Ekane, XE; Gomez, CS; Casillas-Espinosa, PM; Ali, I; Shultz, SR; Andrade, P; Puhakka, N; Staba, RJ; O'Brien, TJ; et al. (Elsevier BV, 2019)Preclinical imaging studies of posttraumatic epileptogenesis (PTE) have largely been proof-of-concept studies with limited animal numbers, and thus lack the statistical power for biomarker discovery. Epilepsy Bioinformatics ...Tieteelliset aikakauslehtiartikkelit
-
Harmonization of pipeline for preclinical multicenter plasma protein and miRNA biomarker discovery in a rat model of post-traumatic epileptogenesis
Kamnaksh, A; Puhakka, N; Ali, I; Smith, G; Aniceto, R; McCullough, J; Das Gupta, S; Ndode-Ekane, XE; Brady, R; Casillas-Espinosa, P; Hudson, M; Santana-Gomez, C; Immonen, R; Abreu, PA; Jones, N; Shultz, S; Staba, RJ; O'Brien, TJ; Agoston, D; Pitkänen, A (Elsevier BV, 2019)The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx) is an international, multicenter, multidisciplinary study aimed at preventing epileptogenesis (EpiBioS4Rx: https://epibios.loni.usc.edu/). One ...Tieteelliset aikakauslehtiartikkelit
-
Harmonization of the pipeline for seizure detection to phenotype post-traumatic epilepsy in a preclinical multicenter study on post-traumatic epileptogenesis
Casillas-Espinosa, PM; Andrade, P; Santana-Gomez, C; Paananen, T; Smith, G; Ali, I; Ciszek, R; Ndode-Ekane, XE; Brady, RD; Tohka, J; Hudson, MR; Perucca, P; Braine, EL; Immonen, R; Puhakka, N; Shultz, SR; Jones, NC; Staba, RJ; Pitkänen, A; O'Brien, TJ (, 2019)Rationale The Epilepsy Bioinformatics Study for Antiepileptogenic Therapy (EpiBioS4Rx) Centre without walls is an NIH funded multicenter consortium. One of EpiBioS4Rx projects is a preclinical post-traumatic epileptogenesis ...Tieteelliset aikakauslehtiartikkelit