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    • FGF21 Contributes to Metabolic Improvements Elicited by Exenatide and Pioglitazone in Patients with Type 2 Diabetes 

      Samms, Ricardo J; Cheng, Christine C; Fourcaudot, Marcel; Heikkinen, Sami; Khattab, Ahmed; Adams, John; Cersosimo, Eugenio; Triplitt, Curtis; Puckett, Curtis; Tsintzas, Kostas; Adams, Andrew Charles; Abdul-Ghani, Muhammad A; DeFronzo, Ralph A; Norton, Luke (American Physiological Society, 2022)
      Fibroblast growth factor 21 (FGF21) is increased acutely by carbohydrate ingestion and is elevated in patients with type 2 diabetes (T2D). However, the physiological significance of increased FGF21 in humans remains largely ...

    • Integrated stress response stimulates FGF21 expression: Systemic enhancer of longevity 

      Salminen A; Kaarniranta K; Kauppinen A (Elsevier BV, 2017)
      FGF21 is a multifunctional metabolic and stress hormone which is normally expressed in liver but cellular stress, e.g. mitochondrial or endoplasmic reticulum (ER) stress, can induce its expression and subsequent secretion ...
      info:eu-repo/semantics/article