Browsing Terveystieteiden tiedekunta by Subject "UDP-sugar"
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Activated hyaluronan metabolism in the tumor matrix - Causes and consequences
(Elsevier BV, 2019)Hyaluronan accumulates in the stroma of several solid tumors and promotes their progression. Both enhanced synthesis and fragmentation of hyaluronan are required as a part of this inflammatory process resembling wound ...Tieteelliset aikakauslehtiartikkelit
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UDP-sugar accumulation drives hyaluronan synthesis in breast cancer
(Elsevier BV, 2018)Increased uptake of glucose, a general hallmark of malignant tumors, leads to an accumulation of intermediate metabolites of glycolysis. We investigated whether the high supply of these intermediates promotes their flow ...Tieteelliset aikakauslehtiartikkelit