Browsing Terveystieteiden tiedekunta by Subject "hyaluronan synthase"
Now showing items 1-4 of 4
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Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2)
(Elsevier BV, 2019)Vesicular trafficking of hyaluronan synthases (HAS1-3) from endoplasmic reticulum (ER) through Golgi to plasma membrane (PM), and either back to endosomes and lysosomes, or out into extracellular vesicles, is important for ...Tieteelliset aikakauslehtiartikkelit
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Elevated expression of hyaluronan synthase 2 associates with decreased survival in diffusely infiltrating astrocytomas
(Springer Nature, 2018)Background Diffusely infiltrating astrocytomas originate from astrocytic glial cells or their precursor cells and are the most common type of brain tumors in adults. In this retrospective study, we investigated the content ...Tieteelliset aikakauslehtiartikkelit
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Hyaluronan synthase 1 : a mysterious enzyme with unexpected functions
(Frontiers Media SA, 2015)Hyaluronan synthase 1 (HAS1) is one of three isoenzymes responsible for cellular hyaluronan synthesis. Interest in HAS1 has been limited because its role in hyaluronan production seems to be insignificant compared to the ...info:eu-repo/semantics/article
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Melanocyte hyaluronan coat fragmentation enhances the UVB-induced TLR-4 receptor signaling and expression of proinflammatory mediators IL-6, IL-8, CXCL-1 and CXCL-10 via NF-kappaB activation
(Elsevier BV, 2019)Skin is constantly exposed to UVR, the most critical risk factor for melanoma development. Hyaluronan is abundant in the epidermal extracellular matrix and may undergo degradation by UVR. It is hypothesized that an intact ...Tieteelliset aikakauslehtiartikkelit