Browsing Terveystieteiden tiedekunta by Subject "immune system"

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    • Vitamin D and evolution: pharmacologic implications 

      Hanel, Andrea; Carlberg, Carsten (Elsevier BV, 2020)
      Vitamin D3 is produced non-enzymatically when the cholesterol precursor 7-dehydrocholesterol is exposed to UV-B, i.e., evolutionary the first function of the molecule was that of an UV-B radiation scavenging end product. ...
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    • Vitamin D Genomics: From In Vitro to In Vivo 

      Carlberg, Carsten (Frontiers Media SA, 2018)
      The vitamin D3 metabolite 1α,25-dihydroxyvitamin D3 [1,25(OH)2D3] is the exclusive high-affinity ligand of the vitamin D receptor (VDR), a transcription factor with direct effects on gene expression. Transcriptome- and ...
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