Now showing items 1-6 of 6

    • Associations of the serum metabolite profile with a healthy Nordic diet and risk of coronary artery disease 

      Noerman, Stefania; Kokla, Marietta; Koistinen, Ville M; Lehtonen, Marko; Tuomainen, Tomi-Pekka; Brunius, Carl; Virtanen, Jyrki K; Hanhineva, Kati (Elsevier BV, 2021)
      Background & aim A healthy Nordic diet (HND) rich in wholegrain cereals, berries, vegetables, and fish, has been associated with a lower risk of cardiovascular disease, but the molecular links remain unclear. Here, we ...
      Tieteelliset aikakauslehtiartikkelit

    • Immunological and Microbiological Profiling of Cumulative Risk Score for Periodontitis 

      Liukkonen, Joonas; Gürsoy, Ulvi K; Könönen, Eija; Akhi, Ramin; Salminen, Aino; Liljestrand, John M; Pradhan-Palikhe, Pratikshya; Pietiäinen, Milla; Sorsa, Timo; Persson, G Rutger; Mäntylä, Päivi; Buhlin, Kåre; Paju, Susanna; Sinisalo, Juha; Hörkkö, Sohvi; Pussinen, Pirkko J (MDPI AG, 2020)
      The cumulative risk score (CRS) is a mathematical salivary diagnostic model to define an individual’s risk of having periodontitis. In order to further validate this salivary biomarker, we investigated how periodontal ...
      Tieteelliset aikakauslehtiartikkelit

    • Metabolic Profiling of High Egg Consumption and the Associated Lower Risk of Type 2 Diabetes in Middle-Aged Finnish Men 

      Noerman, S; Kärkkäinen, O; Mattsson, A; Paananen, J; Lehtonen, M; Nurmi, T; Tuomainen, TP; Voutilainen, S; Hanhineva, K; Virtanen, JK (Wiley, 2019)
      Scope Higher egg intake was previously associated with a lower risk of developing type 2 diabetes (T2D) in the prospective, population‐based Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) in eastern Finland. ...
      Tieteelliset aikakauslehtiartikkelit

    • Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Large-Scale Epidemiology : a Primer on -Omic Technologies 

      Würtz Peter; Kangas Antti J; Soininen Pasi; Lawlor Debbie A; Smith George Davey; Ala-Korpela Mika (Oxford University Press (OUP), 2017)
      Detailed metabolic profiling in large-scale epidemiologic studies has uncovered novel biomarkers for cardiometabolic diseases and clarified the molecular associations of established risk factors. A quantitative metabolomics ...
      info:eu-repo/semantics/article

    • Saliva and serum biomarkers in periodontitis and coronary artery disease 

      Lahdentausta, L; Paju, S; Mäntylä, P; Buhlin, K; Tervahartiala, T; Pietiäinen, M; Alfthan, H; Nieminen, M; Sinisalo, J; Sorsa, T; Pussinen, P (Wiley, 2018)
      Aim Matrix metalloproteinase (MMP)‐8, MMP‐9, tissue inhibitor of matrix metalloproteinase (TIMP)‐1 and myeloperoxidase (MPO) participate in extracellular matrix breakdown both in periodontium and atherosclerotic plaques. ...
      Tieteelliset aikakauslehtiartikkelit

    • Simultaneous analysis by LC-MS/MS of 22 ketosteroids with hydroxylamine derivatization and underivatized estradiol from human plasma, serum and prostate tissue 

      Häkkinen, Merja R; Murtola, Teemu; Voutilainen, Raimo; Poutanen, Matti; Linnanen, Tero; Koskivuori, Johanna; Lakka, Timo; Jääskeläinen, Jarmo; Auriola, Seppo (Elsevier BV, 2019)
      This study describes a validated LC–MS/MS method for assaying 23 steroids within a single run from 150 μl of human plasma, serum or prostatic tissue homogenate. Isotope-labeled steroids were used as internal standards. ...
      Tieteelliset aikakauslehtiartikkelit