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dc.contributor.authorBalkaya, Mustafa G
dc.contributor.authorTrueman, Rebecca C
dc.contributor.authorBoltze, Johannes
dc.contributor.authorCorbett, Dale
dc.contributor.authorJolkkonen, Jukka
dc.date.accessioned2018-08-20T11:54:39Z
dc.date.available2018-08-20T11:54:39Z
dc.date.issued2018
dc.identifier.urihttps://erepo.uef.fi/handle/123456789/6822
dc.description.abstractFunctional recovery after an experimental stroke can be assessed by multiple behavioral tests, however, there is no consensus about which test to use in long-term stroke recovery studies or whether the tests are affected by stroke surgery, post-operative care or behavioral compensation due to repeated testing. This review describes the tests most commonly used to assess motor and sensorimotor function, cognition and mood in stroke animals. Although it is difficult to predict the direction of future research, it may be possible to prevent false-positive results by selecting an appropriate task or a battery of tasks. It is also expected that the upcoming stroke recovery recommendations and the improved dialogue between academy, industry and healthcare professionals will further promote translational success.
dc.language.isoenglanti
dc.publisherElsevier BV
dc.relation.ispartofseriesBEHAVIOURAL BRAIN RESEARCH
dc.relation.urihttp://dx.doi.org/10.1016/j.bbr.2017.07.039
dc.rightsCC BY-NC-ND https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectstroke
dc.subjectanimal models
dc.subjectbehavioral tests
dc.subjectsensorimotor function
dc.subjectcognition
dc.subjectdepression
dc.subjectanxiety
dc.subjectrestoration
dc.titleBehavioral outcome measures to improve experimental stroke research
dc.description.versionfinal draft
dc.contributor.departmentSchool of Medicine / Clinical Medicine
uef.solecris.id48972649en
dc.type.publicationTieteelliset aikakauslehtiartikkelit
dc.rights.accessrights© Elsevier B.V.
dc.relation.doi10.1016/j.bbr.2017.07.039
dc.description.reviewstatuspeerReviewed
dc.format.pagerange161-171
dc.publisher.countryAlankomaat
dc.relation.issn0166-4328
dc.relation.volume352
dc.rights.accesslevelopenAccess
dc.type.okmA2
uef.solecris.openaccessEi


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