Browsing Terveystieteiden tiedekunta by Title
Now showing items 86-105 of 1735
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AMPA receptors in post-mortem brains of Cloninger type 1 and 2 alcoholics: A whole-hemisphere autoradiography study
(Elsevier BV, 2013)Dysfunction of the brain glutamate system has been associated with alcoholism. Ionotropic glutamatergic alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors (AMPARs) play an important role in both neurotransmission ...article
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Amphiphilic Phthalocyanines in Polymeric Micelles: A Supramolecular Approach toward Efficient Third-Generation Photosensitizers
(Royal Society of Chemistry (RSC), 2020)In this paper we describe a straightforward supramolecular strategy to encapsulate silicon phthalocyanine (SiPc) photosensitizers (PS) in polymeric micelles made of poly(ε-caprolactone)-b-methoxypoly(ethylene glycol) ...Tieteelliset aikakauslehtiartikkelit
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Amygdala-orbitofrontal structural and functional connectivity in females with anxiety disorders, with and without a history of conduct disorder
(Springer Nature, 2018)Conduct disorder (CD) and anxiety disorders (ADs) are often comorbid and both are characterized by hyper-sensitivity to threat, and reduced structural and functional connectivity between the amygdala and orbitofrontal ...Tieteelliset aikakauslehtiartikkelit
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Amyloid Plaques Show Binding Capacity of Exogenous Injected Amyloid-ß
(IOS Press, 2017)Amyloid plaques, although inducing damage to the immediately surrounding neuropil, have been proposed to provide a relatively innocuous way to deposit toxic soluble amyloid-β (Aβ) species. Here we address this hypothesis ...Tieteelliset aikakauslehtiartikkelit
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An investigation into the pleiotropic activity of metformin. A glimpse of haemostasis.
(Elsevier BV, 2020)The most characteristic features of type 2 diabetes mellitus (T2DM) are hyperglycaemia and insulin resistance, however, patients with T2DM are at higher risk of cardiovascular disease (CVD) and atherosclerosis. Diabetes, ...Tieteelliset aikakauslehtiartikkelit
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An Isocaloric Nordic Diet Modulates RELA and TNFRSF1A Gene Expression in Peripheral Blood Mononuclear Cells in Individuals with Metabolic Syndrome-A SYSDIET Sub-Study
(MDPI AG, 2019)A healthy dietary pattern is associated with a lower risk of metabolic syndrome (MetS) and reduced inflammation. To explore this at the molecular level, we investigated the effect of a Nordic diet (ND) on changes in the ...Tieteelliset aikakauslehtiartikkelit
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An overview on the associations between health behaviors and brain health in children and adolescents with special reference to diet quality
(MDPI AG, 2020)Unhealthy diet has been associated with overweight, obesity, increased cardiometabolic risk, and recently, to impaired cognition and academic performance. The aim of this review is to provide an overview of the associations ...Tieteelliset aikakauslehtiartikkelit
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Analgesic antipyretic use among young children in the TEDDY study: No association with islet autoimmunity
(2017)Background The use of analgesic antipyretics (ANAP) in children have long been a matter of controversy. Data on their practical use on an individual level has, however, been scarce. There are indications of possible effects ...info:eu-repo/semantics/article
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Analgesic efficacy and pharmacokinetics of epidural oxycodone in pain management after gynaecologic laparoscopy - a randomised, double blind, active control, double-dummy clinical comparison with intravenous administration
(Wiley, 2019)Aims Early pain after laparoscopy is often severe. Oxycodone is a feasible analgesic option after laparoscopy, but there are sparse data on epidural administration. The aim was to evaluate the analgesic efficacy and ...Tieteelliset aikakauslehtiartikkelit
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Analysis of checklists for agricultural safety management
(Institute of Rural Health, 2018)Introduction: The current health and safety management system under the Occupational Health and Safety Act has avoided agriculture in Korea. It is important to consider the various safety systems used in agricultural ...Tieteelliset aikakauslehtiartikkelit
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Analysis of medication errors at a large tertiary care hospital in Saudi Arabia: a retrospective analysis
(Springer Nature, 2017)Background Medication errors (MEs) are common in health care settings and pose a threat for the hospitalized population. Therefore, aspects of MEs were explored in a tertiary setting serving a diverse population. Objective ...article
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Analysis of primary microRNA loci from nascent transcriptomes reveals regulatory domains governed by chromatin architecture
(Oxford University Press (OUP), 2017)Changes in mature microRNA (miRNA) levels that occur downstream of signaling cascades play an important role during human development and disease. However, the regulation of primary microRNA (pri-miRNA) genes remains to ...info:eu-repo/semantics/article
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Analysis of SUMO1-conjugation at Synapses
(2017)SUMO1-conjugation of proteins at neuronal synapses is considered to be a major post-translational regulatory process in nerve cell and synapse function, but the published evidence for SUMO1-conjugation at synapses is ...info:eu-repo/semantics/article
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Analytic Tools for Post-traumatic Epileptogenesis Biomarker Search in Multimodal Dataset of an Animal Model and Human Patients
(Frontiers Media SA, 2018)Epilepsy is among the most common serious disabling disorders of the brain, and the global burden of epilepsy exerts a tremendous cost to society. Most people with epilepsy have acquired forms of the disorder, and the ...Tieteelliset aikakauslehtiartikkelit
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Androgen receptor SUMOylation regulates bone mass in male mice
(Elsevier BV, 2018)The crucial effects of androgens on the male skeleton are at least partly mediated via the androgen receptor (AR). In addition to hormone binding, the AR activity is regulated by post-translational modifications, including ...Tieteelliset aikakauslehtiartikkelit
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Angiogenic gene therapy in cardiovascular diseases: dream or vision?
(Oxford University Press (OUP), 2017)Chronic cardiovascular diseases are significant health problems. Although current treatment strategies have tremendously improved disease management, up to 30% of these patients cannot be successfully treated with current ...info:eu-repo/semantics/article
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Angiogenic profile in the Finnish Genetics of Pre-Eclampsia Consortium (FINNPEC) cohort
(Elsevier BV, 2018)Background Psychopathic traits vary dimensionally in the population and are associated with multiple negative outcomes. The impaired integration theory (IIT) proposes that psychopathic traits are associated with abnormal ...Tieteelliset aikakauslehtiartikkelit
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Anti-bacterial activity of inorganic nanomaterials and their antimicrobial peptide conjugates against resistant and non-resistant pathogens
(Elsevier BV, 2020)This review details the antimicrobial applications of inorganic nanomaterials of mostly metallic form, and the augmentation of activity by surface conjugation of peptide ligands. The review is subdivided into three main ...Tieteelliset aikakauslehtiartikkelit
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Antiandrogens Reduce Intratumoral Androgen Concentrations and Induce Androgen Receptor Expression in Castration-Resistant Prostate Cancer Xenografts
(Elsevier BV, 2018)The development of castration-resistant prostate cancer (CRPC) is associated with the activation of intratumoral androgen biosynthesis and an increase in androgen receptor (AR) expression. We recently demonstrated that, ...Tieteelliset aikakauslehtiartikkelit
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Antiarrhythmic drug therapy among patients presenting to emergency department with symptomatic atrial fibrillation - a prospective nationwide cohort
(Springer Nature, 2017)Background Atrial fibrillation (AF) is a common arrhythmia that causes numerous visits to emergency departments (ED). The aim of the FinFib2 study was to evaluate whether treatment of patients with AF in ED is consistent ...info:eu-repo/semantics/article